The tremors were reportedly felt “widely across” the capital and its suburbs, with car alarms across the city being set off by the shocks.
Data from the US Geological Survey (USGS) confirmed the 4.3 magnitude quake struck 15 miles northeast of Athens at 8.24pm GMT.
The Greek capital is home to more than 3.7 million people.
A separate 4.4 magnitude earthquake hit the Peloponnese region 1 hour earlier. Earthquakes with a magnitude of between 4-4.9 are considered to be “light”, but those in the affected area are likely to notice objects shaking or rattling.
Several earthquakes have hit the region in recent days and the latest seems to be the peak of this activity, Mr Papadopoulos said.
But he did not rule out the possibility of another earthquake. Greece is frequently jolted by earthquakes, the majority of which cause no serious damage.